At what point will someone call Shenanigans? (UPDATED)

I call Shenanigans! Well, not the restaurant, of course. I call shenanigans on this: (It’s a little long, so you can skip it and avoid the headache, or read and get a migraine.)

“My reasons for not vaccinating – what are yours?

Vaccine antigens cause a short term response as measured by antibody count (titer tests). The first problem we encounter is that, when tested after a few weeks those antibodies are, in most people, not present anymore. The next problem is that there is no study proving that a high antibody count actually protects from or prevents disease outside of the lab (real world). The third problem and major issue I have with vaccines is their effect on the immune system. In recent years science has learned that the human immune system is much more complicated than we thought. It is composed of two functional branches or compartments which may work together in a mutually cooperative way or in a mutually antagonistic way depending on the health of the individual.

One branch is the humoral immune system (or Th2 function) which primarily produces antibodies in the blood circulation as a sensing or recognizing function of the immune system to the presence of foreign antigens in the body. The other branch is the cellular or cell-mediated immune system (or Th1 function) which primarily destroys, digests and expels foreign antigens out of the body through the activity of its cells found in the thymus, tonsils, adenoids, spleen, lymph nodes and lymph system throughout the body. This process of destroying, digesting and discharging foreign antigens from the body is known as “the acute inflammatory response” and is often accompanied by the classic signs of inflammation: fever, pain, malaise and discharge of mucus, pus, skin rash or diarrhea.

These two functional branches of the immune system may be compared to the two functions in eating: tasting and recognizing the food on the one hand, and digesting the food and eliminating the food waste on the other hand. In the same way, the humoral or Th2 branch of the immune system “tastes” and recognizes and even remembers foreign antigens and the cellular or Th1 branch of the immune system digests and eliminates the foreign antigens from the body. But just as too much repeated tasting of food will ruin the appetite, so also too much repeated stimulation of the “tasting” humoral immune system by an antigen will inhibit and suppress the digesting and eliminating function of the cellular immune system. In other words, overstimulating antibody production can suppress the acute inflammatory response of the cellular immune system!

This explains the polar opposite relationship between acute discharging inflammations on the one hand and allergies and auto-immune inflammations on the other hand. The more a person has of one, the less he or she will have of the other!

A growing number of scientists believe that the increase in America, Europe, Australia and Japan in allergic and auto-immune diseases (which stimulate the humoral or Th2 branch of the immune system) is caused by the lack of stimulation of the cellular or the Th1 branch of the immune system from the lack of acute inflammatory responses and discharges in childhood. We need to identify the factors which cause this shift in the function of the immune system or which cause allergies and auto-immune diseases in childhood to increase!

If we now return to the original question of the mechanism of action of vaccinations, we find what I believe is the key to the puzzle. A vaccination consists of introducing a disease agent or disease antigen into an individual’s body without causing the disease. If the disease agent provoked the whole immune system into action it wouldcause all the symptoms of the disease! The symptoms of a disease are primarily the symptoms (fever, pain, malaise, loss of function) of the acute inflammatory response to the disease. 

So the trick of a vaccination is to stimulate the immune system just enough so that it makes antibodies and “remembers” the disease antigen but not so much that it provokes an acute inflammatory response by the cellular immune system and makes us sick with the disease we’re trying to prevent! Thus a vaccination works by stimulating very much the antibody production (Th2) and by stimulating very little or not at all the digesting and discharging function of the cellular immune system (Th1).

Vaccine antigens are designed to be “unprovocative” or “indigestible” for the cellular immune system (Th1) and highly stimulating for the antibody-mediated humoral immune system (Th2).

Perhaps it is not difficult to see then why the repeated use of vaccinations would tend to shift the functional balance of the immune system toward the antibody-producing side (Th2) and away from the acute inflammatory discharging side (the cell-mediated side or Th1). This has been confirmed by observation especially in the case of Gulf War Illness: most vaccinations cause a shift in immune function from the Th1 side (acute inflammatory discharging response) to the Th2 side (chronic auto-immune or allergic response).

The outcome of this line of thought is that, contrary to previous belief, vaccinations do not strengthen or “boost” the whole immune system. Instead vaccinations overstimulate the “tasting and remembering” function of the antibody-mediated branch of the immune system (Th2) which simultaneously suppresses the cellular immune system (Th1) thus “preventing” the disease in question. What in reality is prevented is not the disease but the ability of our cellular immune system to manifest, to respond to and overcome the disease. 

Those are my reasons for not vaccinating my children. What are yours?”

This is the guy I told you about before, the one who thinks that his daughter’s type I diabetes was caused by the hepatitis B vaccine she received months earlier, the one who thinks he did “academic research” in writing his book. He claims that he’s not anti-vaccine and that he just wants to inform the public so that the public can make their own decisions. “Inform,” I don’t believe that word means what he thinks it means because that whole bunch of drivel up there, all that stuff, it’s chock-full of misinformation.

“Vaccine antigens cause a short term response as measured by antibody count (titer tests). The first problem we encounter is that, when tested after a few weeks those antibodies are, in most people, not present anymore.”

Not so! Pregnant women are checked for immunity by testing their blood for antibodies (titer tests), measuring the immunoglobulin G levels. Immunoglobulin G (IgG) lasts for a very long time. If I take some blood from you now and do a protein electrophoresis on it (separation of proteins by weight), it will look just like this:

From left to right: Albumin, Alpha 1, Alpha 2, Beta, and Gamma globulins (proteins)
See the gamma globulins all the way on the right? They’re your antibodies. They’ll always be there unless you get sick, in which case you get an infusion of antibodies from a donor to keep you safe from infections. This guy is outright lying when he says that antibodies disappear. They don’t, and that’s why so many vaccines will give you long-lasting immunity.
He then dives into the whole “Th1 vs. Th2” thing, but he gets it completely wrong. Here’s what that system is all about: Th1 is about intracellular pathogens, like viruses. Th2 is about extracellular pathogens, like bacteria and fungi. But anti-vaccine people read that “Mercury depletes glutathione and polarizes toward Th2 dominance” and they went nuts over that. Mercury will do that to people. But there are reasons why this isn’t the case with vaccines.
First, the amount of mercury in vaccines was negligible before manufacturers removed all thimerosal (a mercury-containing compound much like salt is a chlorine-containing compound). Even when we do get thimerosal from a vaccine (usually the flu vaccine nowadays), the amount is negligible, and our bodies are really good at dealing with it. Again, it’s all in the chemistry. But, true to anti-vax ideology, this guy swallows the lie hook, line, and sinker, and it seems to me that he wants you to do the same.
But, hey, if you want to believe him, go ahead and spend hundreds of dollars on a lab test you probably don’t need.

“A growing number of scientists believe that the increase in America, Europe, Australia and Japan in allergic and auto-immune diseases (which stimulate the humoral or Th2 branch of the immune system) is caused by the lack of stimulation of the cellular or the Th1 branch of the immune system from the lack of acute inflammatory responses and discharges in childhood.”

I’d really like to meet these scientists and explain to them that the Th1 component really is being stimulated all the time because we’re under constant bombardment by viruses and other intracellular pathogens. Then again, I don’t think these scientists are a “growing number” of them. Rather, I suspect they are the few anti-vaccine “scientists” who like to claim things that aren’t.

“Thus a vaccination works by stimulating very much the antibody production (Th2) and by stimulating very little or not at all the digesting and discharging function of the cellular immune system (Th1).”

This is how I know this guy knows absolutely nothing about immunology. See, when an antigen is introduced into your body — an antigen that shouldn’t be there — macrophages eat that antigen and then present it to your T helper (the “Th”) cells. So, as you can see, the immune system is involved in everything from antigen response through absorption, digestion, and presentation to T helper cells; to B cells, cells that are not even part of the Th system. It is complex, and that’s why he’s getting it all wrong… All of it! It’s as if he can’t read Wikipedia or something.

“Vaccine antigens are designed to be “unprovocative” or “indigestible” for the cellular immune system (Th1) and highly stimulating for the antibody-mediated humoral immune system (Th2).”

What?! Read this and pay attention to this part on the first page:

“Most antigens and vaccines trigger both B and T cell responses, such that there is no rationale in opposing antibody production (‘humoral immunity’) and T cell responses (‘cellular immunity’). In addition, CD4+ T cells are required for most antibody responses, while antibodies exert significant influences on T cell responses to intracellular pathogens.”

The more he posts on his Facebook page, the more I’m convinced he’s one chicken McNugget short of a Happy Meal®.

UPDATE: A reader of the blog asked me to correct/clarify some things. So I did. I’ve bolded them. Also, he posted this on Facebook to counter the anti-vaccine activist’s rant:

Click to enlarge.

I bet it gets deleted because it’s full of truth.

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3 thoughts on “At what point will someone call Shenanigans? (UPDATED)

  1. @Tina – I bet he also will have no answer as to why older populations had little trouble with H1N1 when it came around. Could it be that they had antibodies to an H1N1 flu from a while back?@Sullivan The Poop – Even I got all sorts of confused trying to explain it. I required advil and EtOH therapy after reading all that BS from this guy.

  2. "Vaccine antigens cause a short term response as measured by antibody count (titer tests). The first problem we encounter is that, when tested after a few weeks those antibodies are, in most people, not present anymore." Yes, that's why my husband still has anti-measles antibodies, detected via titer test, almost 40 years after he got the vaccine.

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